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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'DNA damage-binding protein 1/Protein cereblon' and Ligand = 'BDBM511662'
Target
DNA damage-binding protein 1/Protein cereblon
(Homo sapiens (Human))
TBA
Ligand
BDBM511662
(US11059801, Compound D-29)
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Affinity Data
IC50: 140nM
Assay Description:
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
MCE
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2G44TFM
US Patent