Found 5 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A/B' and Ligand = 'BDBM21691' TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Henan University of Chinese Medicine
Curated by ChEMBL
Henan University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase super-coiling activity using pBR322 DNA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Henan University of Chinese Medicine
Curated by ChEMBL
Henan University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as supercoiled plasmid DNA formation after 30 mins by electrophoretic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+5nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Henan University of Chinese Medicine
Curated by ChEMBL
Henan University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.23E+5nMAssay Description:In vitro antibacterial activity was determined as inhibitory concentration causing 50% DNA-gyrase supercoiling inhibition (SCI)More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Henan University of Chinese Medicine
Curated by ChEMBL
Henan University of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.23E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
