Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A/B' and Ligand = 'BDBM24616'
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Vertex

LigandPNGBDBM24616(1-(6-(4-(Cyclopropylcarbamoyl)-1H-imidazol-1-yl)-4...)copy SMILEScopy InChI
Affinity DataKi: <4nMAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F7TPubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Vertex

LigandPNGBDBM24616(1-(6-(4-(Cyclopropylcarbamoyl)-1H-imidazol-1-yl)-4...)copy SMILEScopy InChI
Affinity DataKi:  12nM ΔG°:  -46.0kJ/molepH: 7.5 T: 2°CAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F7TPubMed