Found 5 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A/B' and Ligand = 'BDBM50366826' TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical Co., Ltd.
Curated by ChEMBL
Wakunaga Pharmaceutical Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of Staphylococcus aureus MS5935 wild type DNA gyrase-mediated supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Staphylococcus aureus wild type DNA gyraseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.45E+5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase S84L mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 2.13E+6nMAssay Description:Inhibition of quinoline-resistant Staphylococcus aureus MS5935 DNA gyrase-mediated supercoiling activityMore data for this Ligand-Target Pair
