Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'DNA polymerase catalytic subunit' and Ligand = 'BDBM50011181'
TargetDNA polymerase catalytic subunit(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Pharmacia Corporation

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44R39PubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1DHNPubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44R39PubMed