Compile Data Set for Download or QSAR
Found 19 Enz. Inhib. hit(s) with Target = 'Delta-type opioid receptor' and Ligand = 'BDBM21025'
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9NN9PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Binding affinity against Opioid receptor delta 1 in P2 membrane preparation of rat brain by [3H]DADLE displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1MHTPubMed
TargetDelta-type opioid receptor(GUINEA PIG)
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.740nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z42X1PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  1.30nM ΔG°:  -50.7kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2TG6PubMed
TargetDelta-type opioid receptor(MOUSE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  1.83nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZPRPubMed
TargetDelta-type opioid receptor(GUINEA PIG)
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZPRPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Inhibition of [3H]DSLET binding to delta 1 opioid receptors in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21R6R37PubMed
TargetDelta-type opioid receptor(MOUSE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:Inhibitory potency against delta Opioid receptor delta 1 in longitudinal muscle preparation of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC0411PubMed
TargetDelta-type opioid receptor(MOUSE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96DBPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]- DADLE binding to Rat brain Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9X82PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7Q5MPubMed
TargetDelta-type opioid receptor(MOUSE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 447nMAssay Description:Agonistic activity towards Opioid receptor delta 1 as inhibitory activity towards electrically stimulated mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9X82PubMed
TargetDelta-type opioid receptor(MOUSE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 447nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7Q5MPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataKd:  2.10nMAssay Description:Affinity against the Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2QKXPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at human DOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64NQRPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataEC50:  54nMAssay Description:Agonist activity at GFP-fused delta opioid receptor (unknown origin) expressed in HEK293 cells assessed as recruitment of beta-arrestin-2 after 10 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96DBPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataEC50:  1.38E+3nMAssay Description:Agonist activity at Rluc-tagged DOR receptor (unknown origin) expressed in human SH-5YSY cells co-expressing RGFP-fused to Gbeta1 assessed as increas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43XD4PubMed