Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50239482'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239482(CHEMBL1683001)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239482(CHEMBL1683001)copy SMILEScopy InChI
Affinity DataIC50: 913nMAssay Description:Inhibition of DGTA1 in mouse C2C12 cells assessed as inhibition of triglyceride formation after 2 hrs by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed