Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM18795'
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMpH: 7.4 T: 2°CAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4G0ZPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B03FPPubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMpH: 7.4 T: 2°CAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4G0ZPubMed