Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50011886'
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50011886(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells. value mentioned is from li...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2000158PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50011886(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2000158PubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50011886(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Compound was tested for its ability to inhibit purified dihydrofolate reductase(DHFR) from L1210/R81 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1ZTRPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50011886(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of dihydrofolate reductase(DHFR) enzyme from human leukemic lymphoblasts.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q1W6JPubMed