Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50041929'
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041929(6-(2,5-Dimethoxy-phenyl)-5-methyl-thieno[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMed