Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50066497'
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50066497(CHEMBL114354 | N*6*-Methyl-N*6*-(5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1HQZPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50066497(CHEMBL114354 | N*6*-Methyl-N*6*-(5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Pneumocystis carinii (pcDHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1HQZPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50066497(CHEMBL114354 | N*6*-Methyl-N*6*-(5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liver (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1HQZPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50066497(CHEMBL114354 | N*6*-Methyl-N*6*-(5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei (lcDHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1HQZPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50066497(CHEMBL114354 | N*6*-Methyl-N*6*-(5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei (lcDHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1HQZPubMed