Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM77567'
TargetDihydrofolate reductase(Escherichia coli)
Uniroyal Chemical Co., Inc.

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  128nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QQJPubMed
TargetDihydrofolate reductase(Escherichia coli)
Uniroyal Chemical Co., Inc.

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  129nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coli (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2S6TPubMed
TargetDihydrofolate reductase(Escherichia coli)
Uniroyal Chemical Co., Inc.

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  129nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JTCPubMed
TargetDihydrofolate reductase(Salmonella enterica subsp. enterica serovar Typhi)
Pomona College

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  129nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92CH4PubMed
TargetDihydrofolate reductase(Escherichia coli)
Uniroyal Chemical Co., Inc.

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  129nMAssay Description:Compound is evaluated for the inhibition of dihydrofolate reductase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WQMPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  427nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Lactobacillus casei (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2S6TPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  427nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4ZB9PubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+3nMAssay Description:Inhibition of dihydrofolate reductase from bovine liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WQMPubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+3nMpH: 7.2Assay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+3nMpH: 7.2Assay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  2.14E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  2.14E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4ZB9PubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM77567(5-(4-Butoxy-benzyl)-pyrimidine-2,4-diamine | 5-[(4...)copy SMILEScopy InChI
Affinity DataKi:  2.14E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed