BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM15350'

Dihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))TBA

BDBM15350(ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...)copy SMILEScopy InChI

IC50: 100nMAssay Description:Inhibition of Plasmodium falciparum HIs6-tagged DHODH expressed in Escherichia coli DH5alpha using L-dihydroorotate as substrate by DCIP-based spectr...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Details Article
BindingDB Entry DOI: 10.7270/Q2JQ13W3

Dihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University of Texas Southwestern Medical Center

BDBM15350(ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...)copy SMILEScopy InChI

IC50: 100nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar

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Details Article
BindingDB Entry DOI: 10.7270/Q21G0JH3PubMed