Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM50379142'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM50379142(CHEMBL2012824 | US8703811, 23)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379142(CHEMBL2012824 | US8703811, 23)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XDSPubMed