Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM92605'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed