Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1' and Ligand = 'BDBM50195238'
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4MTPUS Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5CXQ
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76HN2
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB56W4
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6X5T
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KG7US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q243DZUS Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z321K4PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis

LigandPNGBDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z321K4PubMed