Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1' and Ligand = 'BDBM50195240'
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z321K4PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z321K4PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6X5T
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KG7US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q243DZUS Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5CXQ
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H99949
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB56W4
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76HN2
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4MTPUS Patent