Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM11695'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BJXPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043M1PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160N3PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HT6PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant DPP4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571C1ZPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2WGQPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB18F1PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration against dipeptidyl-peptidase IVMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902380PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55NQQPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of DPP4 in human serum assessed as decrease in p-nitroaniline formation using Gly-Pro-p-nitroanilide as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43XCPPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of DPP4 in presence of 50% human serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z953WPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 16.6nMAssay Description:Inhibition of human DPP4 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2WGQPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of DPP4 in presence of 50% human serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z953WPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972ZMPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251P86PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD70DJPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WZSPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory concentration against Dipeptidyl-peptidase IV [DPP-IV]More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5TJXPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z953WPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 51nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BJHPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 51nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22805V8PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9PDWPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348K74PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant His-tagged DPP4 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QM9PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant DPP4 expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58P3WPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
In DepthDetails DrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of human recombinant DPP4 (39 to 766 residues) using Ala-Pro-AFC as substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N6VPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B050PPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F37PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6VM6PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W5PPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160N3PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43XN8PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataKd:  11nMAssay Description:Binding affinity to human recombinant DPP4 (39 to 766 residues) at 5 uM by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N6VPubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataKd:  2.40nMAssay Description:Binding affinity to human recombinant DPP4 (39 to 766 residues) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N6VPubMedDrugBank