Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 1/2' and Ligand = 'BDBM50072147'
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:AP-1 suppression activity using freshly prepared DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:AP-1 suppression activity using one week old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:AP-1 suppression activity using one month old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:AP-1 suppression activity using two months old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 2.48E+4nMAssay Description:AP-1 suppression activity using six months old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed