Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM50434352'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2610Z7JUS Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DP7PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9NMGPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GDPPubMed