Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1B' and Ligand = 'BDBM50081192'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081192(CHEMBL3421977)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081192(CHEMBL3421977)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed