Compile Data Set for Download or QSAR
Found 21 Enz. Inhib. hit(s) with Target = 'E-selectin' and Ligand = 'BDBM50450369'
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for the Selectin E binding activity.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN38CCPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Ability to inhibit the binding to Selectin E immobilized on SPA beads of radiolabeled HL-60 cell membrane was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8SBB
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibitory activity against binding of Selectin E to human recombinant AGP (alpha-1 acid glycoprotein) containing sLex derivativeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73F71PubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for its ability to inhibit the binding to recombinant human Selectin E immobilized on SPA beads of radiolabeled HL60 cell membran...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SMM
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Ability to inhibit sialyl Lewis X binding to Selectin E was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J8C
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibitory activity against human chimeric E-selectin-IgMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZWWPubMed
TargetE-selectin(Mus musculus)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+5nMAssay Description:In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP253KPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibitory concentration against blocking of E-selectin during migration of inflammatory cells to inflammatory siteMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0P0BPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+5nMAssay Description:Displacement of sialyl Lewis X (sLex) from selectin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BHNPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+5nMAssay Description:In vitro inhibitory activity of compound was determined against Selectin E binding by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP46M8PubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibitory concentration against E-selectinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP03BBPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin B recep...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GG8
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+6nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in Selectin EMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9JR1PubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+6nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in Selectin EMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9JR1PubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+6nMAssay Description:In vitro inhibition of HL60 (human leukemia) cell binding to human recombinant e-selectin.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56KCPPubMed
TargetE-selectin(Mus musculus)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+6nMAssay Description:Compound was tested for its ability to inhibit sialyl Lewis X dependent binding of HL-60 cells to Selectin E fusion proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81D24
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+6nMAssay Description:Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin E-IgG fusion proteins by 50%.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03G4PubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin E and HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28C9WSCPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin E and HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28C9WSCPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin E and HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28C9WSCPubMed
TargetE-selectin(Homo sapiens (Human))
Universit£ de Montr£al

Curated by ChEMBL
LigandPNGBDBM50450369(SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...)copy SMILEScopy InChI
Affinity DataKd:  1.00E+6nMAssay Description:Affinity of compound to Selectin E was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8SBB