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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM31287'
Target
E3 ubiquitin-protein ligase Mdm2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM31287
(1,4-benzodiazepine-2,5-dione scaffold, 52)
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Affinity Data
IC50: 810nM
pH: 7.5 T: 2°C
Assay Description:
Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q23F4MZJ
PubMed