Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM427195'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427195(US10544132, Example 136 | US10981898, Example 137 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1N06US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427195(US10544132, Example 136 | US10981898, Example 137 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD14WTUS Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427195(US10544132, Example 136 | US10981898, Example 137 ...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD14WTUS Patent