Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50008816'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50008816(CHEMBL3236663)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862J0JPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50008816(CHEMBL3236663)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in buffer ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862J0JPubMed