Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50448932'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50448932(CHEMBL3125531 | US9296736, 307 | US9593129, Exampl...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M960ZPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50448932(CHEMBL3125531 | US9296736, 307 | US9593129, Exampl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay in presence of 15% h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M960ZPubMed