Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP' and Ligand = 'BDBM50401490' TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori
Curated by ChEMBL
Fondazione IRCCS Istituto Nazionale dei Tumori
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori
Curated by ChEMBL
Fondazione IRCCS Istituto Nazionale dei Tumori
Curated by ChEMBL
Affinity DataIC50: 293nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
