Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50396040'
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50396040(CHEMBL1823895)copy SMILEScopy InChI
Affinity DataIC50: 593nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human LN229 cells expressing HRE-AP reporter gene preincubated for 1 hr under normoxia condition fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WH0PubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50396040(CHEMBL1823895)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HIF1 transcriptional activity in human LN229 cells expressing VEGF-HRE-V6R and coexpressing luciferase, lac Z gene incubated for 1 hr i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52SGDPubMed