Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM4460'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4460(3-(3-Cyano-6,7-dimethoxyquinolin-4-ylamino)benzami...)copy SMILEScopy InChI
Affinity DataIC50: 7.69E+3nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2D9MPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4460(3-(3-Cyano-6,7-dimethoxyquinolin-4-ylamino)benzami...)copy SMILEScopy InChI
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GXNPubMed