Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM4595'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4595(4-anilinoquinazoline deriv. 17 | 6-Substituted 4-A...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19WBPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4595(4-anilinoquinazoline deriv. 17 | 6-Substituted 4-A...)copy SMILEScopy InChI
Affinity DataIC50: 339nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN93TSPubMed