Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM4777'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4777(4-Anilinopyrido[3,4-d]pyrimidine 3 | CHEMBL51659 |...)copy SMILEScopy InChI
Affinity DataIC50: 0.910nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19WBPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4777(4-Anilinopyrido[3,4-d]pyrimidine 3 | CHEMBL51659 |...)copy SMILEScopy InChI
Affinity DataIC50: 0.910nMAssay Description:Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56HZGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4777(4-Anilinopyrido[3,4-d]pyrimidine 3 | CHEMBL51659 |...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor (EGFR) in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56HZGPubMed