Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50084026'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund

Curated by ChEMBL
LigandPNGBDBM50084026(CHEMBL3425662)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of GST-tagged human recombinant EGFR catalytic domain (668 to 1210 amino acids) T790M/L858R mutant expressed in Sf9 cells pre-incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9STHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund

Curated by ChEMBL
LigandPNGBDBM50084026(CHEMBL3425662)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant EGFR catalytic domain (668 to 1210 amino acids) L858R mutant expressed in Sf9 cells pre-incubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9STHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund

Curated by ChEMBL
LigandPNGBDBM50084026(CHEMBL3425662)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged human EGFR kinase domain (702 to 1016 residues) expressed in Sf9 cells pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9STHPubMed