Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50451309'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50451309(CHEMBL4215496)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of EGFR E746_A750 deletion/T790M mutant in human growth-resistant PC9 cells assessed as reduction in cell viability after 72 hrs by MTT as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z183XPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50451309(CHEMBL4215496)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of EGFR E746_A750 deletion mutant in human PC9 cells assessed as reduction in cell viability after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z183XPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50451309(CHEMBL4215496)copy SMILEScopy InChI
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of EGFR in human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z183XPubMed