Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50505839' TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co KG
Curated by ChEMBL
Boehringer Ingelheim RCV GmbH & Co KG
Curated by ChEMBL
Affinity DataIC50: 519nMAssay Description:Inhibition of GST-fusion tagged EGFR L858R/T790M/C797S triple mutant (unknown origin) (696 to 1022 residues) expressed in insect cells assessed as de...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Mus musculus)
Boehringer Ingelheim RCV GmbH & Co KG
Curated by ChEMBL
Boehringer Ingelheim RCV GmbH & Co KG
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co KG
Curated by ChEMBL
Boehringer Ingelheim RCV GmbH & Co KG
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged wild type EGFR expressed in baculovirus expression system assessed as decrease in phosphorylation of ULigh...More data for this Ligand-Target Pair
