Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [T790M]' and Ligand = 'BDBM5447' TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
Affinity DataIC50: 22.5nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
3D Structure (crystal)TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
