Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM19969'
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataKi:  14.5nM ΔG°:  -44.3kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416VB9PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataKi:  14.5nM ΔG°:  -44.3kJ/mole EC50:  32.5nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014SVPubMed