Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM301005'
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM301005(5-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-6-...)copy SMILES
Affinity DataIC50: 0.126nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 18 to 22 hrs by immuno-fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80PDPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM301005(5-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-6-...)copy SMILES
Affinity DataIC50: 0.170nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QJ9US Patent
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM301005(5-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-6-...)copy SMILES
Affinity DataIC50: 2nMAssay Description:Displacement of fluorescent labelled fluormone ES2 from human recombinant GST tagged ER alpha LBD ( 282 to 595 residues) expressed in baculovirus inf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80PDPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM301005(5-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-6-...)copy SMILES
Affinity DataIC50: 2nMAssay Description:The assay principle is that ER alpha-LBD (GST) is added to a fluorescent ligand to form a receptor/fluorophore complex. A terbium-labelled anti-GST a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QJ9US Patent