Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM306734'
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306734(3-(3,5- difluoro-4- ((1R,3R)-2-(2- fluoro-2-methyl...)copy SMILES
Affinity DataIC50: 0.140nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306734(3-(3,5- difluoro-4- ((1R,3R)-2-(2- fluoro-2-methyl...)copy SMILES
Affinity DataIC50: 0.240nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306734(3-(3,5- difluoro-4- ((1R,3R)-2-(2- fluoro-2-methyl...)copy SMILES
Affinity DataIC50: 0.260nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306734(3-(3,5- difluoro-4- ((1R,3R)-2-(2- fluoro-2-methyl...)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306734(3-(3,5- difluoro-4- ((1R,3R)-2-(2- fluoro-2-methyl...)copy SMILES
Affinity DataIC50: 2.20nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306734(3-(3,5- difluoro-4- ((1R,3R)-2-(2- fluoro-2-methyl...)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent