Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM306757'
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306757(N-(2-(4-((1R,3R)-2-(2,2-Difluoroethyl)-3-methyl-2,...)copy SMILES
Affinity DataIC50: 0.150nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM306757(N-(2-(4-((1R,3R)-2-(2,2-Difluoroethyl)-3-methyl-2,...)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P62M5US Patent