Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM368197'
TargetEstrogen receptor(Homo sapiens (Human))
University of Arizona at Tucson

LigandPNGBDBM368197((-)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:MCF-7 cells were adjusted to a concentration of 40,000 cells per mL in RPMI containing 10% FBS and 20 mM HEPES. 16 microliters of the cell suspension...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Arizona at Tucson

LigandPNGBDBM368197((-)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Arizona at Tucson

LigandPNGBDBM368197((-)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha protein level after 4 hrs by InCell Western assayMore data for this Ligand-Target Pair