Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM368203'
TargetEstrogen receptor(Homo sapiens (Human))
Seragon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM368203(US10227334, Example (S)-3-(3-Hydroxyphenyl)-4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha protein level after 4 hrs by InCell Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P34ZNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Seragon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM368203(US10227334, Example (S)-3-(3-Hydroxyphenyl)-4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP55SCPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Seragon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM368203(US10227334, Example (S)-3-(3-Hydroxyphenyl)-4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:MCF-7 cells were adjusted to a concentration of 40,000 cells per mL in RPMI containing 10% FBS and 20 mM HEPES. 16 microliters of the cell suspension...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN97Z7US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Seragon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM368203(US10227334, Example (S)-3-(3-Hydroxyphenyl)-4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP55SCPubMed