Found 3 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50233215' TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
