Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50437046'
TargetEstrogen receptor(Homo sapiens (Human))
the University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to GST-tagged human ER alpha ligand-binding domain by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171GJPubMed
TargetEstrogen receptor(Homo sapiens (Human))
the University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme in Hog plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S184N9PubMed
TargetEstrogen receptor(Homo sapiens (Human))
the University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171GJPubMed
TargetEstrogen receptor(Homo sapiens (Human))
the University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996QPPubMed
TargetEstrogen receptor(Homo sapiens (Human))
the University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human MCF7 cells assessed as inhibition of E2-induced response by dual luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170Q8PubMed
TargetEstrogen receptor(Homo sapiens (Human))
the University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170Q8PubMed
TargetEstrogen receptor(Homo sapiens (Human))
the University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171GJPubMed