Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50503111'
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.0794nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as downregulation of ER alpha receptor expression measured after 18 to 22 hrs by immuno...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.530nMAssay Description:Antagonist activity at estrogen receptor in human T47D cells incubated for 18 hrs by ultra high sensitivity luminescence reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of fluorescent labelled fluormone ES2 from human recombinant GST tagged ER alpha LBD ( 282 to 595 residues) expressed in baculovirus inf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB