Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Estrogen receptor beta' and Ligand = 'BDBM50169743'
TargetEstrogen receptor beta(Homo sapiens (Human))
SignalGene Inc.

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataKi:  1.39nMAssay Description:In vitro displacement of 0.5 nM [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9Q5JPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
SignalGene Inc.

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at estrogen receptor beta ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RQRPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
SignalGene Inc.

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MQRPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
SignalGene Inc.

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human estrogen receptor 2 using tritiated estradiol incubated for 3 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JDBPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
SignalGene Inc.

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]-E2 from estrogen receptor-beta (unknown origin) by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H7QPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
SignalGene Inc.

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 44.1nMAssay Description:Binding affinity to human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RZWPubMed