Found 3 Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 2-alpha kinase 3' and Ligand = 'BDBM50396531' TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
In DepthDetails
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of thapsigargin-induced autophosphorylation of PERK in human A549 cells after 2 hrs by Western blottingMore data for this Ligand-Target Pair
