Found 3 Enz. Inhib. hit(s) with Target = 'Excitatory amino acid transporter 1' and Ligand = 'BDBM50327884' TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of EAAT1 (unknown origin) transiently expressed in COS1 cells by [14C]glutamate based uptake assayMore data for this Ligand-Target Pair
