Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Farnesyl pyrophosphate synthase' and Ligand = 'BDBM12579'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataKi:  303nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataKi:  368nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M93Z8PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M93Z8PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M93Z8PubMed