Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM269334'
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM269334(2-(2-fluoro-4-(6-fluoronaphthalen-2-yl)phenyl)-1-(...)copy SMILEScopy InChI
Affinity DataIC50: 30.2nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H134CBUS Patent
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM269334(2-(2-fluoro-4-(6-fluoronaphthalen-2-yl)phenyl)-1-(...)copy SMILEScopy InChI
Affinity DataIC50: 30.2nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PJBUS Patent