Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM269339'
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM269339((R)-4,4-dimethyl-2-(3-methyl-4'-(1-methyl-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 53.7nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H134CBUS Patent
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM269339((R)-4,4-dimethyl-2-(3-methyl-4'-(1-methyl-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 53.7nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PJBUS Patent